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COMMENTARY
Year : 2019  |  Volume : 2  |  Issue : 1  |  Page : 19-21

Resurgence of role of radiotherapy in neoadjuvant treatment of pancreatic cancer


Department of Radiation Oncology, Kokilaben Dhirubhai Ambani Hospital, Mumbai, India

Correspondence Address:
Dr. Kaustav Talapatra
Department of Radiation Oncology, Kokilaben Dhirubhai Ambani Hospital, Four Bungalows, Andheri (W), Mumbai 400 053
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JCO.JCO_23_18

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Borderline resectable pancreatic cancer (BRPC) is a clinically distinguished malignancy. With limited role of aggressive surgical intervention, neoadjuvant treatment is warranted. Various studies and their meta-analysis addressing this issue have shown limited benefit. However, recently two prospective multiple randomized trials have evaluated benefit of neoadjuvant chemoradiotherapy in BRPC with a positive clinical response. This article gives a brief insight into these studies and discusses future prospects for role of radiation in neoadjuvant setting in pancreatic cancer.


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