• Users Online: 363
  • Print this page
  • Email this page
CASE REPORT
Year : 2019  |  Volume : 2  |  Issue : 1  |  Page : 22-25

Pseudoangiomatous stromal hyperplasia presenting as an enlarging breast mass: A case report


1 Department of General Surgery, Amrita Institute of Medical Sciences, Kochi, Kerala, India
2 Department of Pathology, Amrita Institute of Medical Sciences, Kochi, Kerala, India
3 Department of Radiology, Amrita Institute of Medical Sciences, Kochi, Kerala, India

Correspondence Address:
Dr. Mala M Sharma
Department of General Surgery, Amrita Institute of Medical Sciences, Ponekkara PO, Edapally, Kochi, Kerala
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/JCO.JCO_25_18

Get Permissions

Pseudoangiomatous stromal hyperplasia (PASH) is an occasional histological finding in the breast tissue, which rarely presents as a clinical mass. We here report a case of progressively increasing breast lump that had radiological ambiguous findings but on excision proved to be PASH on histology and immunohistochemistry (IHC). On microscopy, PASH has to be distinguished from low-grade vascular tumors as stromal spaces in it mimic the endothelium-lined vascular spaces. In view of nonspecific radiological picture, histopathological confirmation by core needle or excision is mandatory. It may coexist with in situ or invasive breast malignancies also. IHC with stromal and vascular markers is the key to diagnosis of PASH; also these tumors show positivity with progesterone markers pointing to endocrine stimulation as a possible etiology. In asymptomatic PASH, expectant management is indicated; however, in symptomatic and enlarging masses, surgical treatment should be preferred.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed653    
    Printed82    
    Emailed0    
    PDF Downloaded82    
    Comments [Add]    

Recommend this journal