Journal of Current Oncology

CASE REPORT
Year
: 2018  |  Volume : 1  |  Issue : 2  |  Page : 89--93

Clinical pearls in pediatric anesthetic considerations for peripheral blood stem cell transplant and lacunae in our current knowledge


Shagun B Shah1, Ajay K Bhargava1, Sangeeta Bhagat1, Dinesh Bhurani2, Narendra Agrawal2 
1 Department of Anaesthesiology Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India
2 Department of Hemato-Oncology and Bone Marrow Transplant, Rajiv Gandhi Cancer Institute and Research Centre, Rohini, New Delhi, India

Correspondence Address:
Shagun B Shah
H. No: 174�175, Ground Floor, Pocket 17, Sector 24, Rohini, New Delhi 110085
India

Clinical introduction of peripheral blood stem cell transplant (PBSCT) has replaced bone marrow as a stem cell source in 99% autologous and 75% allogeneic transplantation cases. Incompliant pediatric donors require general anesthesia for PBSCT. Whether the CD34-positive (CD34+) stem cell yield from PBSC donor is affected by age, weight, and sex of donor and type/duration of anesthesia is not very clear from the current literature. These factors may have significant clinical implications as is evident from the poor yield (0.11 million/kg CD34+ cells) on the second day of stem cell harvest from our 2-year-old donor.


How to cite this article:
Shah SB, Bhargava AK, Bhagat S, Bhurani D, Agrawal N. Clinical pearls in pediatric anesthetic considerations for peripheral blood stem cell transplant and lacunae in our current knowledge.J Curr Oncol 2018;1:89-93


How to cite this URL:
Shah SB, Bhargava AK, Bhagat S, Bhurani D, Agrawal N. Clinical pearls in pediatric anesthetic considerations for peripheral blood stem cell transplant and lacunae in our current knowledge. J Curr Oncol [serial online] 2018 [cited 2024 Mar 29 ];1:89-93
Available from: http://www.https://journalofcurrentoncology.org//article.asp?issn=2589-8892;year=2018;volume=1;issue=2;spage=89;epage=93;aulast=Shah;type=0